Endocrine Abstracts

Introduction: Type 1 autoimmune polyglandular syndrome is a rare entity, presenting typically during childhood and comprising a variable combination of autoimmune endocrine and non-endocrine diseases that differ in their immunological features. This phenotypical heterogeneity may difficult the identification of this syndrome.Clinical case: 33 year-old female, presenting with secondary amenorrhoea at the age of 13, and by that date diagnosed with hypergon...

Introduction: Cyclic Cushing syndrome (CCS) involves rhythmic fluctuations in ACTH secretion resulting in a cyclic variation of adrenal steroid production.Case presentation: A 37-year-old woman was referred to our Pituitary Clinic in 1999, for evaluation of galactorrhea and irregular menses that had started four months ago. She also complained of depression, facial hirsutism, alopecia and progressive obesity. Blood pressure was normal. Endocrinological e...

Introduction: There are limited data on the incidence and prevalence of pituitary adenomas (PA). Although classically considered rare, systematic assessments from autopsy and radiological studies have shown a prevalence of 17% in the general population.Objective: We describe the epidemiologic of PA in Braga, the third most populous district of Portugal (860 000 inhabitants, 2673 km2), over the last 20 years.Methods: We r...

Introduction: Adrenal surgical series are scarce in the literature. We aim to present a single institution consecutive case series and to establish a radiologic-pathological correlation.Material and methods: A retrospective, observational and descriptive study was conducted by searching the Pathology database for surgically removed adrenal lesions. Cases were matched with the Imagiology database. Ultrasound, CT and MRI images were then reviewed by the sa...

Giant prolactinomas are uncommon, with some individual case reports described in the literature, but with few series documenting treatment outcomes. They represent a therapeutic challenge, since restoring normoprolactinemia, eugonadism and reducing tumour size may not be realistic goals. Specific complications may also arise during treatment that change the initial management plans. The authors describe a case of a 28-year-old male with visual impairment and behavioural change...

Introduction: Prolactinomas are the most common pituitary adenomas in paediatric patients, except in the first decade of life, when ACTH secreting adenomas are more frequent.Objective: Analysis of clinical, diagnostic and therapeutic data of prolactinomas in paediatric age.Methods: Retrospective study of 15 patients whose symptoms began before 18 years of age.Results: In girls, secondary amenorrhea (58.3%) an...

Introduction: Subacute thyroiditis is usually a self-limited pathology, possibly of viral aetiology, defined by cervical pain and sometimes systemic symptoms. Its association with autoimmune diseases doesn’t seem to be more frequent than in the general population.Clinical case: Clinical findings of thyrotoxicosis with 3 weeks of evolution associated with anterior cervical pain and fever up to 38 °C. The patient presented with recurrent mouth so...

Introduction: Positive radiotracer uptake by the thyroid gland can occur in PET-CT. It’s meaning has led to conflicting results mainly resulting from small studies.Objective: We aim to present a large single institution consecutive case series.Material and methods: Observational, descriptive and retrospective study of the PET-CT scans performed between the years 2000–2017. We searched the word thyroid in the computer imag...